石虎
姓名：石虎
职称：副教授
介绍：石虎，博士学位，致力于解决生物体系和材料体系中分子和原子层面上的关键科学问题。在Sci. Adv.、Nat. Commun.、J. Am. Chem. Soc.、Angew、Chem、Adv. Funct. Mater.等国际权威学术期刊发表学术论文130余篇。获得“Research Excellence Award”（2017韩国）、国家优秀自费留学生奖（2018韩国）和山西青年创业奖（2022）。目前担任Frontiers in Chemistry副主编等职位。指导大学生参加竞赛获得国家级奖项3项和省级奖项8项。（热烈欢迎有志于科研事业的学子保送、报考本实验室研究生，2026年学硕计划招收：1名，专硕计划招收：1名）
学习与工作经历：
2023/01 – 至今 山西大学，PA电子，副教授
2018/01 – 2022/12 山西大学，PA电子，讲师
2017/06 – 2017/12 韩国成均馆大学和韩国基础科学研究院，博士后
2013/09 – 2017/05 韩国成均馆大学，化学院，博士
2010/09 – 2013/06 济南大学，PA电子，硕士
2005/09 – 2009/06 巢湖学院，PA电子，学士
讲授课程：
分子动力学模拟、计算化学、生物化学和能源收集
研究方向：
1. Computational Biochemistry and Computational Material Science
1) Protein Folding, Misfolding, and Aggregation Mechanisms
2) Material Functionalization and Related Simulations
3) Machine Learning Applications
2. Energy Storage and Related Applications
1) Experimental Material Functionalization
2) Related Energy Applications
主持科研项目：
1. 国家级项目1项
2. 省级项目4项
3. 企业合作项目7项
代表性论文：（近五年，#并列一作；*通讯作者）
42. Hu Shi*, Jing Li, Yue Sun, Lisha Wang, Li Yan, Xin Pu*
Histidine behaviors effect on β-sheet-rich dimer formation of Tau R3 fragment: New insights on primary nucleation processes Biophys. Chem. 2026, 334, 107602
41. Zihan Gao, Miaomiao Cui, Anning Song, Huirong Zhang, Liang Wei, Yanqiang Lei, Aniu Qian,* Hu Shi,* and Qijun Sun* Synergistic Co/Fe/Zn−Nx Active Sites on Microporous Carbon Nanotubes for High Power-Density Flexible Aqueous Magnesium−Air Batteries Nano Lett. 2026, 26, 713−722
40. Chenhui Bai, Yuxiu Yao, Saeed Ahmed Khan, Jing Li, Fang Yi, Jie Zhang*, Hu Shi*, Hulin Zhang*
Configurational entropy change-driven enhancement of thermoelectric performance in PVA-based hydrogel thermogalvanic cells J. Power Sources 2026, 665, 239060
39. Jing Li, Yue Sun, Lisha Wang, Hancheng Gong, and Hu Shi* New Insights into the Structural Rearrangement and Aggregation Properties of Aβ-PrP Cross-Seeding Modulated by Histidine Behaviors ACS Chem. Neurosci. 2025, 16, 3567−3576
38. Xiaoting Hao, Jing Li, Bing Zhang, Xiaoming Zhang,* Xian Liu, Hu Shi,* and Hengquan Yang* Transforming Crowded Coacervates into Multi-Compartmental Hybrid Microreactors for Practical Enzymatic Catalysis Angew. Chem. 2025, e202502479
37. Yue Sun and Hu Shi* New Insights on Protein Folding and Misfolding: Histidine Behaviors ACS Chem. Neurosci. 2025, 16, 1418−1419
36. Huimin Bai, Jie Wang, Jianghong Zhao,* Hongxia Zhang, Hu Shi*, and Pengju Yang* Intermolecular proton-coupled electron transfer reconstructs aggregates for near-infrared-light driven hydrogen evolution J. Mater. Chem. C, 2025, 13, 3242
35. Fangfang Zhang*, Yupeng Song, Yihe Qiu, Yue Sun, Xiaohui Luo, Chaoyi Jin, Shutian Zhu, Hu Shi*, Guocan Jiang*, Yongteng Qian* Regulation of interfacial microenvironment by introducing Co atoms into MoSP compounds with enhanced catalytic activity for overall water splitting J. Alloys Compd. 1010 (2025) 177916
34. Yongteng Qian*, Yue Sun, Fangfang Zhang, Yupeng Song, Xiaohui Luo, Lin Shen, Minkyun Sohn, Hu Shi*, Dae Joon Kang* Controlling the microenvironment by introducing dual metal atoms into ZIF-L to enhance hydrogen evolution activity Appl. Surf. Sci. 2025, 684, 161791
33. Xiaoting Hao, ShuoWang, Xiaoming Zhang, Zhiqiang Ma, Ming Zhang, Hu Shi*, Hengquan Yang* Engineering enzyme conformation within liquid-solid hybrid microreactors for enhanced continuous-flow biocatalysis Nat. Commun. 2024, 15, 10440
32. Yue Sun, Yaru Shi, Jing Li, Aniu Qian,* and Hu Shi* New Hypothesis on Enhancing β‑Sheet Formation during the Tau Fragment Dimer Transition from a Flexible Monomer: Insights into Primary Nucleation Processes by Histidine Behaviors J. Phys. Chem. Lett. 2024, 15, 10763−10768
31. Hu Shi,* Mengyao Ma, Yue Sun, Miaomiao Cui, and Aniu Qian* Surface ‒OH Termination-Reduced Ti3C2Tx Pseudo-capacitors with Reinforced Ionic Liquid Accessibility to Achieve High Energy Density Adv. Funct. Mater. 2024, 2410006
30. Yue Sun, Yaru Shi, Changgui Li, and Hu Shi* Histidine Protonation Behaviors on Structural Properties and Aggregation Properties of Aβ(1−42) Mature Fibril: Approaching by Edge Effects J. Phys. Chem. B 2024, 128, 7341
29. Yunxia Wang, Yicheng Xu, Rui Zhang, Jing Li, Yujie Cong, Ruipeng Li, Xiaoyu Wang, Hu Shi,* Shaowei Wang,* and Liheng Feng* Tuning Molecular Assembly Behavior to Amplify Sonodynamic Activity of Porphyrin for Efficient Antibacterial Therapy Biomater. Sci., 2024,12, 4440-4451
28. Yongteng Qian*, Yue Sun, Fangfang Zhang, Xiaohui Luo, Kangning Li, Lin Shen, Hu Shi*, Dae Joon Kang, Huan Pang* In situ construction of layered transition metal phosphides/sulfides heterostructures for efficient hydrogen evolution in acidic and alkaline media J. Chem. Eng. 2024, 490, 151693
27. Changzhen Wang*, Xueqing Hai, Juan Bai, Yaru Shi, Liyuan Jing, Hu Shi*, Zhou Chen, Yongxiang Zhao*
Elucidating the atomic stacking structure of nickel phyllosilicate catalysts and their consequences on efficient hydrogenation of 1,4-butynediol to 1,4-butanediol J. Chem. Eng. 2024, 488, 150723
26. Aniu Qian,* Miaomiao Cui, Yue Sun, Guangyu Wang, Yuehui Hao, Chengli Yang, and Hu Shi* NiCo2O4 Nanowires Immobilized on Nitrogen-Doped Ti3C2Tx for High-Performance Wearable Magnesium–Air Batteries Small 2024, 2310398
25. Yaru Shi, Yue Sun, Changgui Li, Shuo Wang, Jinping Wang,* and Hu Shi* Edge Substitution Effects of Histidine Tautomerization Behaviors on the Structural Properties and Aggregation Properties of Aβ(1−42) Mature Fibril ACS Chem. Neurosci. 2024, 15, 1055
24. Yaru Shi, Yue Sun, and Hu Shi* Effect of Histidine Behaviors on Structural Properties of Human Islet Amyloid Peptides ChemistrySelect 2024, 9, e202302452
23. Rong Sheng Li, Jiahui Liu, Cong Wen, Yaru Shi, Jian Ling, Qiue Cao, Lei Wang, Hu Shi*, Cheng Zhi Huang*, Na Li* Transformable nano-antibiotics for mechanotherapy and immune activation against drug-resistant Gramnegative bacteria Sci. Adv. 2023, 9, eadg9601
22. Yongteng Qian*, Jianmin Yu, Fangfang Zhang, Zhengxin Fei, Hu Shi*, Dae Joon Kang, Huan Pang*
Hierarchical binary metal sulfides nanoflakes decorated on graphene with precious-metal-like activity for water electrolysis J. Chem. Eng. 470 (2023) 144372
21. Yue Sun, Changgui Li, Jinping Wang* and Hu Shi* The effect of histidine behaviors on the structural properties of Ab(1–42) peptide in protonation stage one, two, and three Phys. Chem. Chem. Phys., 2023, 25, 18346
20. Yue Sun, Changgui Li, Jinping Wang,* and Hu Shi* New Hypothesis Insight of Structural Properties on Four Tau Peptide Fragments in Alzheimer’s Disease: Origin from the Histidine Behaviors Chem. Eur. J. 2023, e202300868
19. Tian He, Ya Zhang, Hongxia Zhang, Jianghong Zhao,* Hu Shi,* Hengquan Yang, and Pengju Yang*
Aggregation-Induced Structural Symmetry Breaking Promotes Charge Separation for Efficient Photocatalytic Hydrogen Production ChemSusChem 2023, e202300500
18. Pengju Yang,* Qi Zhang, Ya Zhang, Hongxia Zhang, Jianghong Zhao, Hu Shi,* Linfeng Liang, Yamin Huang, Zhanfeng Zheng, and Hengquan Yang* Aggregation Triggers Red/Near-Infrared Light Hydrogen Production of Organic Dyes with High Efficiency ACS Catal. 2023, 13, 3723
17. Guangyu Wang, Hao Wu, Yiming Liu, Yiwei Pang, Junsheng Hao, Fangqin Cheng, Aniu Qian* and Hu Shi* Surface fluorine preservation dependence of Ti3C2Tx MXene for high electrochemical properties in ionic liquid electrolytes Chem. Commun., 2023, 59, 1369
16. Hu Shi,* Yue Sun, Zeshuai Yao, and Min Bai* New Insights into the Structural and Binding Properties on Aβ Mature Fibrils Due to Histidine Protonation Behaviors ACS Chem. Neurosci. 2023, 14, 218−225
15. Jing Wang, Ying Zhang, Wenhao Wang, Lina Yin, Mo Xie, Jin Yong Lee, Hu Shi,* and Hongguang Liu* How Does Molecular Diameter Correlate with the Penetration Barrier of Small Gas Molecules on Porous Carbon-Based Monolayer Membranes? J. Phys. Chem. A 2023, 127, 517−526
14. Yue Sun, Zeshuai Yao, Guangyu Wang, Lisha Wang, Min Bai*, Hu Shi* Concentration Effect, Structural Properties, and Driving Force on Aβ28 Dimerization with and without Zn2+ Cooperation: Learning from Replica Exchange Sampling Chemphyschem 2022, e202200710
13. Yue Sun, Zeshuai Yao, Hu Shi* Structural properties of Aβ(1–40) peptide in protonation stage of one, two, and three: New insights from the histidine protonation behaviors Int. J. Biol. Macromol. 2022, 223, 1556–1561
12. Jianghong Zhao,* Rihui Mu, Ya Zhang, Zhidong Yang, Hongxia Zhang, Hu Shi,* Min Zhang, Zhanfeng Zheng and Pengju Yang* A general acetic acid vapour etching strategy to synthesize layered carbon nitride with carbon vacancies for efficient photoredox catalysis J. Mater. Chem. A, 2022, 10, 16873
11. Pengju Yang,* Ya Zhang, Hongxia Zhang, Jianghong Zhao, Zhihong Wei, Hu Shi,* Zhanfeng Zheng, Yamin Huang, and Hengquan Yang* Hydrogen-Bonded Aggregates Featuring n→π* Electronic Transition for Efficient Visible-Light-Responsive Photocatalysis ACS Catal. 2022, 12, 6276−6284
10. Fangfang Zhang, Lisha Wang, Mose Park, Kyeong-Youn Song, Hoon Choi, Hu Shi*, Hoo-Jeong Lee*, Huan Pang* Nickel sulfide nanorods decorated on graphene as advanced hydrogen evolution electrocatalysts in acidic and alkaline media J. Colloid Interface Sci. 2022, 608, 2633–2640
9. Yongteng Qian, Jianmin Yu, Ya Zhang, Fangfang Zhang, Yingbo Kang, Chenliang Su, Hu Shi,* Dae Joon Kang,* and Huan Pang* Interfacial Microenvironment Modulation Enhancing Catalytic Kinetics of Binary Metal Sulfides Heterostructures for Advanced Water Splitting Electrocatalysts Small Methods 2021, 2101186
8. Sima Kalhor, Mahmoud Zarei*, Mohammad Ali Zolfigol*, Hassan Sepehrmansourie, Davood Nematollahi*, Saber Alizadeh*, Hu Shi* & Jalal Arjomandi Anodic electrosynthesis of MIL‑53(Al)‑N(CH2PO3H2)2 as a mesoporous catalyst for synthesis of novel (N‑methyl‑pyrrol)‑pyrazolo[3,4‑b] pyridines via a cooperative vinylogous anomeric based oxidation Sci. Rep. 2021, 11, 19370
7. Rong Sheng Li, Jiahui Liu, Hu Shi,* Ping Ping Hu, Yao Wang, Peng Fei Gao, Jian Wang, Moye Jia, Hongwei Li, Yuan Fang Li, Chengde Mao,* Na Li,* and Cheng Zhi Huang* Transformable Helical Self-Assembly for Cancerous Golgi Apparatus Disruption Nano Lett. 2021, 21, 8455−8465
6. Hao Li Abbas Salimi Francis Kirby B. Burnea Hu Shi* Jin Yong Lee* Insight into the histidine tautomerism effect on heterodimers of Aβ40 Bull Korean Chem Soc. 2021, 1
5. Pengju Yang,* Ruonan Wang, Hongxia Zhang,* Jianghong Zhao, Peng Wang, Hu Shi* and Hengquan Yang* A semi-crystalline carbonaceous structure as a wide-spectrum-responsive photocatalyst for efficient redox catalysis Chem. Commun., 2021, 57, 5086
4. Pengju Yang*, Lei Shang, Jianghong Zhao, Ming Zhang, Hu Shi*, Hongxia Zhang*, Hengquan Yang*. Selectively constructing nitrogen vacancy in carbon nitrides for efficient syngas production with visible light. Appl. Catal. B 2021, 297, 120496
3. Hu Shi,* Lisha Wang, Zeshuai Yao, Jin Yong Lee, and Wei Guo*. Role of the English (H6R) Mutation on the Structural Properties of Aβ40 and Aβ42 Owing to the Histidine Tautomeric Effect. ACS Chem. Neurosci., 2021, 12, 2705
2. Sima Kalhor, Mahmoud Zarei,*, Hassan Sepehrmansourie, Mohammad Ali Zolfigol*, Hu Shi*, Jinping Wang, Jalal Arjomandi, Masoumeh Hasani, Romana Schirhagl. Novel uric acid-based nano organocatalyst with phosphorous acid tags: Application for synthesis of new biologically-interest pyridines with indole moieties via a cooperative vinylogous anomeric based oxidation. Mol. Catal. 2021, 507, 111549
1. Wenjun Xie, Weicong Huang, Lingzhi Tu, Hu Shi* and Hongguang Liu*. Design of one-dimensional organic semiconductors with high intrinsic electron mobilities: lessons from computation. J. Mater. Chem. C, 2021, 9, 3620
授权专利：
授权专利3项
