姓名：晏湖明

职称：讲师

联系方式：yanhm@sxu.edu.cn

介绍：晏湖明，1992.08，山西大学分子科学研究所讲师，主要开展分子荧光探针生物成像研究。在J. Am. Chem. Soc.、Anal. Chem.等期刊发表SCI论文10篇，获2023年山西省科学技术一等奖（自然科学奖，第五完成人），授权2项发明专利，2023年获宝钢优秀学生奖、研究生国家奖学金。

学习与工作经历：

2025/06—至今 山西大学 分子科学研究所 讲师

2022.09—2025.07 山西大学 分子科学研究所 博士

2018.09—2021.07 山西大学 分子科学研究所 硕士

2013.09—2017.07 山西大同大学 化学与环境工程学院 学士

工作职责：无

研究方向：分子工程荧光探针用于生物示踪成像

讲授课程：无

主持科研项目：无

代表性论文：

1. Huming Yan, Ningyu Zhang, Yuting Wang, Junping Wang, Bin Huo, Fangjun Huo*, and Caixia Yin*, Fluorescence Imaging of Neuroblastocyte Differentiation and Parkinson’s Brain Tissue Lesions Examined by a Norepinephrine Activated Molecular Probe, Analytical Chemistry, 2025, 97, 16329−16337.

2. Huming Yan, Yuting Wang, Fangjun Huo*, Caixia Yin*, Fast-Specific Fluorescent Probes to Visualize Norepinephrine Signaling Pathways and Its Flux in the Epileptic Mice Brain, Journal of the American Chemical Society, 2023, 145, 3229−3237.

3. Huming Yan^#, Fangjun Huo^#, Yongkang Yue, Jianbin Chao, and Caixia Yin*, Rapid Reaction, Slow Dissociation Aggregation, and Synergetic Multicolor Emission for Imaging the Restriction and Regulation of Biosynthesis of Cys and GSH, Journal of the American Chemical Society, 2021, 143, 318−325.

4. Huming Yan, Fangjun Huo, Yongkang Yue, Jianbin Chao, Caixia Yin*, A practical pH-compatible fluorescent sensor for hydrazine in soil, water and living cells, Analyst, 2020, 145, 7380.

5. Huming Yan, Yongkang Yue, Caixia Yin*, Yongbin Zhang, Jianbin Chao, Fangjun Huo*, A water-soluble fluorescent probe for the detection of thiophenols in water samples and in cells imaging, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2020, 229, 117905.

6. Yuting Wang, Huming Yan, Fangjun Huo*, Caixia Yin*, Cys fluorescent probe precisely modified by fluorine revealing oxidative stress mechanism in Parkinson’s disease, Nano Today, 2024, 57, 102401.

7. Yuting Wang, Huming Yan, Yongkang Yue, Yongbin Zhang, Fangjun Huo*, Fangqin Cheng*, Caixia Yin*, GSH and H₂O₂ dynamic correlation in the ferroptosis pathways revealed by engineered probe in tumor and kidney injury, Chemical Engineering Journal, 2023, 464, 142496.

8. Xiyuan Zhang, Huming Yan, Fangjun Huo, Jianbin Chao, Caixia Yin*, Dual-emission NIR fluorescent probe sensitive response biological microenvironment and sulfur dioxide, Sensors & Actuators: B. Chemical, 2021, 344, 130244.

9. Xingwei Li, Huming Yan, Fangjun Huo*, Yongbin Zhang, Le Zhang, Haixian Ren, Caixia Yin*, A near-infrared fluorescent probe for in situ imaging of SO₂ flux in drug-induced liver injury, Analyst, 2023, 148, 2465.

10. Ying Wen, Zefeng Hu, Wenhao Tian, Huming Yan, Fangjun Huo, Caixia Yin*, A dual-cascade-activatable molecular probe with microenvironment-adapted performance for accurate differentiation of hepatopathy, Biomaterials, 2025, 322, 123382.

授权专利：

1. 阴彩霞 晏湖明 霍方俊，一种香豆素衍生物Th-HM1及其合成方法和应用，国家发明专利，ZL 2020 1 1014086.5，授权日期：2021.09.28;

2. 晏湖明 阴彩霞 霍方俊，2-（环己-2-烯-1-亚基）丙二腈衍生物及其合成方法和应用，国家发明专利，ZL 2022 1 1485929.9，授权日期：2024.03.12